Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729750 | 0.96 | SYK (0.61) | SYK | |
| SCHEMBL2719026 | 0.91 | SYK (0.57) | SYK | |
| SCHEMBL2728249 | 0.86 | SYK (0.53) | SYK | |
| SCHEMBL10272211 | 0.83 | SYK (0.49) | SYK | |
| SCHEMBL2715816 | 0.80 | SYK (0.58) | SYK | |
| SCHEMBL2716506 | 0.79 | SYK (0.69) | SYK | |
| SCHEMBL2716728 | 0.78 | SYK (0.56) | SYK | |
| SCHEMBL14956011 | 0.75 | SYK (0.67) | SYK | |
| SCHEMBL735847 | 0.75 | SYK (1.00) | SYK | |
| SCHEMBL2717957 | 0.75 | SYK (0.57) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061415-A1 | OXYPYRIMIDINES AS SYK MODULATORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | WO | claimed |
| WO-2012061415-A1 | OXYPYRIMIDINES AS SYK MODULATORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |