Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30056639 | 1.00 | GRM5 (0.37) | GRM5PKMALDH1A1KDM4EPOLB | |
| SCHEMBL27166107 | 0.89 | PROKR1 (0.41) | GRM5ALDH1A1MAPTSMN1; SMN2AKR1C3 | |
| SCHEMBL27166169 | 0.83 | DPP4 (0.39) | GRM5ELANEDPP4NOTUM | |
| SCHEMBL30828304 | 0.83 | DPP4 (0.37) | GRM5AKR1C3ELANECYP1A2CYP2D6 | |
| SCHEMBL30055057 | 0.83 | NOTUM (0.33) | GRM5AKR1C3ELANEDPP4NOTUM | |
| SCHEMBL27166154 | 0.83 | NOTUM (0.33) | GRM5AKR1C3ELANEDPP4NOTUM | |
| SCHEMBL27166088 | 0.81 | ELANE (0.39) | AKR1C3ELANECYP1A2DPP4 | |
| SCHEMBL27166196 | 0.81 | NOTUM (0.36) | ALDH1A1MAPTSMN1; SMN2ELANEDPP4 | |
| SCHEMBL30057055 | 0.81 | PKM (0.40) | GRM5PKMALDH1A1AKR1C3CYP1A2 | |
| SCHEMBL27166123 | 0.81 | PKM (0.40) | GRM5PKMALDH1A1AKR1C3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334289-A1 | NOVEL HETEROCYCLIC COMPOUNDS, COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF | Organon R&D Finland Ltd (FI) | 2024-03-13 | — | — | EP | disclosed |