SCHEMBL27166261

SCHEMBL27166261

CCOCCOCCOc1ccc(C[C@H](N)CO)nc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 2/20 0.39
PPARG P37231 3/20 0.38
PPARA Q07869 3/20 0.38
ACACB O00763 1/20 0.38
THRA P10827 1/20 0.38
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SLCO1B3 Q9NPD5 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
APP P05067 1/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27166331 1.00 NCF1 (0.39) NCF1PPARGPPARAACACBTHRA
Hydrochloric Acid SCHEMBL27166252 0.99 NCF1 (0.39) NCF1PPARGPPARAACACBTHRA
Hydrochloric Acid SCHEMBL27166328 0.99 NCF1 (0.39) NCF1PPARGPPARAACACBTHRA
SCHEMBL9446753 0.83 NCF1 (0.43) NCF1PPARGPPARAACACB
SCHEMBL27166321 0.82 ACACB (0.50) NCF1ACACBTHRAALDH1A1MEN1
SCHEMBL27166319 0.82 ACACB (0.50) NCF1ACACBTHRAALDH1A1MEN1
SCHEMBL27166284 0.82 ACACB (0.50) NCF1ACACBTHRAALDH1A1MEN1
SCHEMBL27166249 0.82 ACACB (0.50) NCF1ACACBTHRAALDH1A1MEN1
Hydrochloric Acid SCHEMBL30804763 0.81 ACACB (0.49) NCF1ACACBTHRAALDH1A1MEN1
SCHEMBL27268878 0.80 ACACB (0.51) NCF1PPARGPPARAACACBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024052549-A1 NEW CONTRAST AGENTS FOR USE IN DIAGNOSTIC IMAGING BAYER AKTIENGESELLSCHAFT (DE) 2024-03-14 WO disclosed
WO-2024052549-A1 NEW CONTRAST AGENTS FOR USE IN DIAGNOSTIC IMAGING BAYER AKTIENGESELLSCHAFT (DE) 2024-03-14 WO disclosed
EP-4335840-A1 NEW CONTRAST AGENTS FOR USE IN DIAGNOSTIC IMAGING Bayer Aktiengesellschaft (DE) 2024-03-13 EP disclosed