Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 10/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29135479 | 0.88 | BTK (0.46) | BTKADAMTS5SMN1; SMN2MMP2GFER | |
| Hydrochloric Acid SCHEMBL27167131 | 0.81 | BRD4 (0.43) | BTKBRD4 | |
| Hydrochloric Acid SCHEMBL30057196 | 0.81 | BRD4 (0.43) | BTKBRD4 | |
| SCHEMBL23777784 | 0.70 | ADAMTS5 (0.56) | ADAMTS5SMN1; SMN2MMP2GFERLMNA | |
| SCHEMBL23777622 | 0.70 | GFER (0.70) | SMN1; SMN2GFERTP53LMNAMAPT | |
| SCHEMBL23777843 | 0.70 | ADAMTS5 (0.56) | ADAMTS5SMN1; SMN2MMP2GFERLMNA | |
| SCHEMBL23777624 | 0.70 | GFER (0.70) | SMN1; SMN2GFERTP53LMNAMAPT | |
| SCHEMBL23777709 | 0.70 | GFER (0.70) | SMN1; SMN2GFERTP53LMNAMAPT | |
| SCHEMBL23777781 | 0.70 | ADAMTS5 (0.56) | ADAMTS5SMN1; SMN2MMP2GFERLMNA | |
| SCHEMBL19876259 | 0.70 | BTK (0.70) | BTKBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4333982-A1 | PKC-THETA MODULATORS | Exscientia Al Limited (GB) | 2024-03-13 | — | — | EP | disclosed |