Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2713347 | 0.84 | SYK (0.56) | SYKLMNA | |
| SCHEMBL1849097 | 0.84 | SYK (0.64) | SYK | |
| SCHEMBL2714314 | 0.79 | SYK (0.73) | SYKLMNA | |
| SCHEMBL2714305 | 0.79 | SYK (0.73) | SYKLMNA | |
| SCHEMBL2714322 | 0.79 | SYK (0.57) | SYK | |
| SCHEMBL2715102 | 0.79 | SYK (0.57) | SYK | |
| SCHEMBL2716764 | 0.78 | SYK (0.63) | SYKLMNA | |
| SCHEMBL2716760 | 0.78 | SYK (0.63) | SYKLMNA | |
| SCHEMBL2713245 | 0.78 | SYK (0.54) | SYK | |
| SCHEMBL2715466 | 0.77 | SYK (0.41) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635556-A2 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | Portola Pharmaceuticals, Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012061418-A2 | BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-10 | — | — | WO | disclosed |