Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 10/20 | 0.62 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29976664 | 1.00 | DDB1 (0.62) | DDB1CRBNHTR2AKCNH2CYP2D6 | |
| SCHEMBL27168231 | 1.00 | DDB1 (0.62) | DDB1CRBNHTR2AKCNH2CYP2D6 | |
| SCHEMBL27167811 | 0.95 | DDB1 (0.63) | DDB1CRBNKCNH2HRH4HRH3 | |
| SCHEMBL29976687 | 0.95 | DDB1 (0.63) | DDB1CRBNKCNH2HRH4HRH3 | |
| SCHEMBL27167809 | 0.95 | DDB1 (0.63) | DDB1CRBNKCNH2HRH4HRH3 | |
| SCHEMBL27167868 | 0.95 | DDB1 (0.63) | DDB1CRBNKCNH2HRH4HRH3 | |
| SCHEMBL31160706 | 0.91 | CRBN (0.68) | DDB1CRBN | |
| SCHEMBL23551326 | 0.89 | DDB1 (0.65) | DDB1CRBNKCNH2HRH4HRH3 | |
| SCHEMBL31160940 | 0.88 | DDB1 (0.53) | DDB1CRBNKCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL23538499 | 0.88 | DDB1 (0.64) | DDB1CRBNKCNH2HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4333899-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF BRUTON'S TYROSINE KINASE | Biogen MA Inc. (US) | 2024-03-13 | — | — | EP | disclosed |