SCHEMBL31160706

SCHEMBL31160706

Cn1nc(N2CCC(=O)NC2=O)c2ccc(C3CNC3)cc21

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 19/20 0.68
▸ DDB1 Q16531 18/20 0.68
▸ SSTR4 P31391 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29976687 0.92 DDB1 (0.63) CRBNDDB1
SCHEMBL27167809 0.92 DDB1 (0.63) CRBNDDB1
SCHEMBL27167811 0.92 DDB1 (0.63) CRBNDDB1
SCHEMBL27167868 0.92 DDB1 (0.63) CRBNDDB1
SCHEMBL29976664 0.91 DDB1 (0.62) CRBNDDB1
SCHEMBL27167653 0.91 DDB1 (0.62) CRBNDDB1
SCHEMBL27168231 0.91 DDB1 (0.62) CRBNDDB1
SCHEMBL23551326 0.89 DDB1 (0.65) CRBNDDB1
Hydrochloric Acid SCHEMBL29744718 0.88 DDB1 (0.64) CRBNDDB1
Hydrochloric Acid SCHEMBL23538499 0.88 DDB1 (0.64) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062426-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF DIFFERENTIATED THERAPEUTICS INC (US) 2026-03-05 — — US disclosed
EP-4673449-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF Differentiated Therapeutics Inc (US) 2026-01-07 — — EP disclosed
WO-2024182555-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF DIFFERENTIATED THERAPEUTICS, INC. (US) 2024-09-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062426-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF CCNA1, CCNE1, CCNA2 CRBN 429/4885DDB1 308/4885SSTR4 1980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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