Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.62 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25229938 | 1.00 | DDB1 (0.62) | DDB1CRBNMEN1KMT2ASTS | |
| SCHEMBL29744807 | 0.90 | DDB1 (0.63) | DDB1CRBNMAPTNPC1ALDH1A1 | |
| SCHEMBL31443811 | 0.90 | DDB1 (0.63) | DDB1CRBNMAPTNPC1ALDH1A1 | |
| SCHEMBL23538523 | 0.90 | DDB1 (0.63) | DDB1CRBNMAPTNPC1ALDH1A1 | |
| SCHEMBL23538718 | 0.89 | DDB1 (0.62) | DDB1CRBNMAPTKDM4ETHRB | |
| SCHEMBL31444244 | 0.89 | DDB1 (0.62) | DDB1CRBNMAPTNPC1ALDH1A1 | |
| SCHEMBL29946886 | 0.89 | DDB1 (0.62) | DDB1CRBNMAPTKDM4ETHRB | |
| SCHEMBL23539198 | 0.89 | DDB1 (0.62) | DDB1CRBNMAPTKDM4ETHRB | |
| SCHEMBL23538572 | 0.89 | DDB1 (0.62) | DDB1CRBNMAPTKDM4ETHRB | |
| SCHEMBL29535240 | 0.89 | DDB1 (0.62) | DDB1CRBNMAPTKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4333899-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF BRUTON'S TYROSINE KINASE | Biogen MA Inc. (US) | 2024-03-13 | — | — | EP | disclosed |