SCHEMBL2716841

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2715348	0.91	EPHX2 (0.44)	SCN9AEPHX2RIPK1KDM4EMEN1
	SCHEMBL2715345	0.90	SCN9A (0.52)	SCN9AEPHX2MAPTGSK3BTRPV1
	SCHEMBL2715704	0.90	EPHX2 (0.43)	SCN9AEPHX2TRPV1RIPK1ADORA3
	SCHEMBL2714534	0.89	EPHX2 (0.42)	SCN9AEPHX2MAPTTRPV1RIPK1
	SCHEMBL2716938	0.89	GSK3B (0.55)	SCN9AEPHX2MAPTGSK3BTRPV1
	SCHEMBL2716257	0.89	SCN9A (0.47)	SCN9AMAPTGSK3BTRPV1RIPK1
	SCHEMBL2715358	0.86	EPHX2 (0.40)	SCN9AEPHX2RIPK1KDM4EMEN1
	SCHEMBL2715214	0.86	EPHX2 (0.44)	SCN9AEPHX2MAPTTRPV1PTGES
	SCHEMBL2715665	0.86	SCN9A (0.51)	SCN9AEPHX2MAPTGSK3BPTGES
	SCHEMBL2715619	0.84	EPHX2 (0.46)	EPHX2MAPTTRPV1RIPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.