SCHEMBL2715345

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2718000	0.91	EPHX2 (0.46)	SCN9AEPHX2RIPK1
	SCHEMBL2716841	0.90	SCN9A (0.52)	SCN9AEPHX2MAPTGSK3BPTGES
	SCHEMBL2716536	0.89	GSK3B (0.57)	SCN9AEPHX2MAPTGSK3BPTGES
	SCHEMBL2716954	0.89	EPHX2 (0.45)	SCN9AEPHX2PTGESTRPV1RIPK1
	SCHEMBL2715665	0.88	SCN9A (0.51)	SCN9AEPHX2MAPTGSK3BPTGES
	SCHEMBL2714889	0.88	EPHX2 (0.44)	SCN9AEPHX2TRPV1RIPK1KDM4E
	SCHEMBL2716601	0.88	SCN9A (0.47)	SCN9AMAPTGSK3BPTGESADORA3
	SCHEMBL2717371	0.87	EPHX2 (0.44)	SCN9AEPHX2MAPTGSK3BRIPK1
	SCHEMBL2715645	0.86	SCN9A (0.51)	SCN9AEPHX2MAPTGSK3BADORA3
	SCHEMBL2715208	0.86	SCN9A (0.53)	SCN9AEPHX2MAPTGSK3BPTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.