Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28205257 | 0.87 | ELANE (0.40) | ELANEALDH1A1NAPRTPARP1SLC22A12 | |
| SCHEMBL25909815 | 0.78 | HSP90AA1 (0.44) | ELANEALDH1A1KDM4E | |
| SCHEMBL15157548 | 0.76 | GRIN2B (0.41) | ALDH1A1HPGDKDM4ECXCR3 | |
| SCHEMBL2718108 | 0.75 | FGFR1 (0.38) | ALDH1A1NAPRTGAASMN1; SMN2 | |
| SCHEMBL28881483 | 0.74 | PARP1 (0.44) | PARP1SLC22A12SLC22A6ABCG2 | |
| SCHEMBL15569948 | 0.72 | PARP1 (0.31) | PARP1 | |
| SCHEMBL2964956 | 0.72 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL22772829 | 0.71 | ALDH1A1 (0.34) | ALDH1A1NAPRTSIRT6 | |
| SCHEMBL17464104 | 0.70 | FGFR1 (0.37) | ALDH1A1HPGDALKGAASMN1; SMN2 | |
| SCHEMBL17714320 | 0.70 | RPS6KA5 (0.36) | ELANEALDH1A1SLC22A12ALKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337660-A1 | HETEROCYCLIC DERIVATIVES AS CAMKK2 INHIBITORS | Bristol-Myers Squibb Company (US) | 2024-03-20 | — | — | EP | disclosed |