Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 5/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | FPR3 | P25089 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.40 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30074465 | 1.00 | FPR2 (0.48) | FPR2USP30SCN9AJAK2JAK1 | |
| SCHEMBL27171876 | 1.00 | FPR2 (0.48) | FPR2USP30SCN9AJAK2JAK1 | |
| SCHEMBL27171944 | 0.95 | USP30 (0.48) | FPR2USP30FPR3PDE4BTRPV3 | |
| SCHEMBL29279272 | 0.95 | USP30 (0.48) | FPR2USP30FPR3PDE4BTRPV3 | |
| SCHEMBL30074441 | 0.95 | USP30 (0.48) | FPR2USP30FPR3PDE4BTRPV3 | |
| SCHEMBL29279276 | 0.87 | SCN9A (0.45) | FPR2USP30SCN9AJAK2JAK1 | |
| SCHEMBL30074442 | 0.87 | SCN9A (0.45) | FPR2USP30SCN9AJAK2JAK1 | |
| SCHEMBL27171864 | 0.85 | KDM4E (0.42) | — | |
| SCHEMBL31386029 | 0.80 | PDE4B (0.53) | USP30SCN9AJAK2JAK1PDE4B | |
| SCHEMBL14862490 | 0.79 | EED (0.48) | USP30JAK2JAK1PDE4BHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337660-A1 | HETEROCYCLIC DERIVATIVES AS CAMKK2 INHIBITORS | Bristol-Myers Squibb Company (US) | 2024-03-20 | — | — | EP | disclosed |