Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720247 | 0.85 | TDP1 (0.35) | MEN1KMT2AUSP2ALDH1A1TP53 | |
| SCHEMBL16412190 | 0.80 | USP2 (0.47) | MEN1KMT2AGAAUSP2ALDH1A1 | |
| SCHEMBL28128355 | 0.79 | CA1 (0.44) | CA12CA14CA1CA2DGAT1 | |
| SCHEMBL2443295 | 0.77 | CA12 (0.36) | CA12CA14CA1CA2DGAT1 | |
| SCHEMBL2443294 | 0.77 | CA12 (0.36) | CA12CA14CA1CA2DGAT1 | |
| SCHEMBL27542596 | 0.77 | CA12 (0.36) | CA12CA14CA1CA2DGAT1 | |
| SCHEMBL25166303 | 0.76 | CTSK (0.45) | CA1CA2CTSSCTSK | |
| SCHEMBL21004186 | 0.76 | CTSK (0.45) | CA1CA2CTSSCTSK | |
| SCHEMBL28926772 | 0.76 | CA1 (0.55) | CA1CA2CTSSCTSK | |
| SCHEMBL28537327 | 0.76 | FOLH1 (0.40) | CA12CA14CA1CA2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337211-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| CN-117337178-A | Compounds and uses thereof | 福宏治疗公司 | 2024-01-02 | — | — | CN | disclosed |