Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27176402 | 0.82 | SMN1; SMN2 (0.61) | KCNA5SMN1; SMN2GAASLC6A2SLC6A4 | |
| SCHEMBL30326956 | 0.82 | SMN1; SMN2 (0.61) | KCNA5SMN1; SMN2GAASLC6A2SLC6A4 | |
| SCHEMBL4120932 | 0.81 | SMN1; SMN2 (0.45) | KCNA5SMN1; SMN2GAASLC6A2SLC6A4 | |
| SCHEMBL6585155 | 0.80 | SLC6A2 (0.48) | KCNA5SMN1; SMN2GAASLC6A2SLC6A4 | |
| SCHEMBL22645056 | 0.79 | SLC6A2 (0.47) | KCNA5SMN1; SMN2GAASLC6A2SLC6A4 | |
| SCHEMBL29112655 | 0.76 | KDM4E (0.46) | KCNA5SMN1; SMN2GAASLC6A2SLC6A4 | |
| SCHEMBL5386880 | 0.76 | SMN1; SMN2 (0.53) | KCNA5SMN1; SMN2GAASLC6A2SLC6A4 | |
| SCHEMBL1381154 | 0.76 | KCNA5 (0.55) | KCNA5SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20465414 | 0.75 | KCNA5 (0.45) | KCNA5SMN1; SMN2GAASLC6A2SLC6A4 | |
| SCHEMBL18400269 | 0.75 | KCNA5 (0.45) | KCNA5SMN1; SMN2GAASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4341261-A1 | AXL COMPOUNDS | Arcus Biosciences, Inc. (US) | 2024-03-27 | — | — | EP | disclosed |