Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.68 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.63 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.61 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27181085 | 0.88 | GRM4 (0.65) | KMT2AMEN1TSHRGRM4GPR27 | |
| SCHEMBL27181171 | 0.85 | GRM4 (0.68) | KMT2AMEN1GRM4GPR27ALDH1A1 | |
| SCHEMBL30926464 | 0.85 | GRM4 (0.68) | KMT2AMEN1GRM4GPR27ALDH1A1 | |
| SCHEMBL30926935 | 0.82 | KMT2A (0.61) | KMT2AMEN1TSHRSTING1BDKRB1 | |
| SCHEMBL27180994 | 0.82 | KMT2A (0.61) | KMT2AMEN1TSHRSTING1BDKRB1 | |
| SCHEMBL23226380 | 0.80 | STING1 (0.78) | KMT2AMEN1TSHRGRM4STING1 | |
| SCHEMBL30926907 | 0.80 | GPR27 (0.66) | KMT2AMEN1GPR27LMNAMAPT | |
| SCHEMBL27180149 | 0.80 | GPR27 (0.66) | KMT2AMEN1GPR27LMNAMAPT | |
| SCHEMBL6351422 | 0.79 | HTT (0.67) | KMT2AMEN1TSHRGRM4GPR27 | |
| SCHEMBL1970027 | 0.79 | GRM4 (1.00) | KMT2AMEN1GRM4GPR27BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580404-A2 | SULFONAMIDE APYRASE INHIBITORS | Texas Crop Science, Inc. (US) | 2025-07-09 | — | — | EP | claimed |
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | claimed |
| WO-2024050041-A2 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE (US) | 2024-03-07 | — | — | WO | claimed |
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | KMT2A 2544/4885MEN1 4795/4885TSHR 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.