Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300776 | 0.76 | ALDH1A1 (0.34) | CDC7RAB9ATSHRIKBKBALDH1A1 | |
| SCHEMBL2299934 | 0.75 | LIMK1 (0.42) | LIMK1CLK1CDC7PDE4APDE4B | |
| SCHEMBL2303335 | 0.75 | CYP1A2 (0.32) | LMNARAB9AALDH1A1HPGD | |
| SCHEMBL278692 | 0.75 | CDC7 (0.51) | LIMK1CLK1CDC7DBF4LMNA | |
| SCHEMBL5729400 | 0.72 | KDM4E (0.46) | LIMK1CLK1CDC7DBF4LMNA | |
| SCHEMBL2303768 | 0.71 | KDM4A (0.41) | LIMK1ALDH1A1PARP1 | |
| SCHEMBL2302794 | 0.71 | KDM4A (0.44) | LIMK1ALDH1A1HPGDPARP1PDPK1 | |
| SCHEMBL14780491 | 0.70 | LIMK1 (0.53) | LIMK1CLK1CDC7DBF4IKBKB | |
| SCHEMBL3084745 | 0.67 | AXL (0.53) | SMN1; SMN2PARP1PDPK1CA12ALOX15 | |
| SCHEMBL10309423 | 0.67 | LIMK1 (0.45) | LIMK1CLK1CDC7DBF4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209775-A | Detection of methylation status | 潘塔贝斯公司 | 2023-06-02 | — | — | CN | claimed |
| EP-4172361-A1 | DETECTION OF METHYLATION STATUS | Pentabase APS (DK) | 2023-05-03 | — | — | EP | claimed |
| US-10988810-B2 | Methods and materials for detection of mutations | PENTABASE APS (DK) | 2021-04-27 | — | — | US | claimed |
| US-20190085400-A1 | METHODS AND MATERIALS FOR DETECTION OF MUTATIONS | PENTABASE APS (DK) | 2019-03-21 | — | — | US | claimed |
| EP-2004847-A2 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | Pentabase Aps (DK) | 2008-12-24 | — | — | EP | claimed |
| WO-2007104318-A2 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2007-09-20 | — | — | WO | claimed |
| US-20250346955-A1 | DETECTION OF METHYLATION STATUS | PENTABASE APS (DK) | 2025-11-13 | — | — | US | disclosed |
| EP-4172361-B1 | DETECTION OF METHYLATION STATUS | PENTABASE AS (DK) | 2024-08-07 | — | — | EP | disclosed |
| CN-116209775-A | Detection of methylation status | 潘塔贝斯公司 | 2023-06-02 | — | — | CN | disclosed |
| EP-4172361-A1 | DETECTION OF METHYLATION STATUS | Pentabase APS (DK) | 2023-05-03 | — | — | EP | disclosed |
| US-20220205024-A1 | MELTING TEMPERATURE METHODS, KITS AND REPORTER OLIGO FOR DETECTING VARIANT NUCLEIC ACIDS | PENTABASE APS (DK) | 2022-06-30 | — | — | US | disclosed |
| CN-114286865-A | Melting temperature methods, kits and reporter oligonucleotides for detecting variant nucleic acids | 潘塔贝斯公司 | 2022-04-05 | — | — | CN | disclosed |
| EP-3969614-A1 | MELTING TEMPERATURE METHODS, KITS AND REPORTER OLIGO FOR DETECTING VARIANT NUCLEIC ACIDS | PentaBase ApS (DK) | 2022-03-23 | — | — | EP | disclosed |
| US-20090192178-A1 | mGluR1 ANTAGONISTS AS THERAPEUTIC AGENTS | SCHERING CORPORATION | 2009-07-30 | — | — | US | disclosed |
| US-20090082336-A1 | mGluR1 Antagonists as Therapeutic Agents | SCHERING CORPORATION | 2009-03-26 | — | — | US | disclosed |
| US-7485648-B2 | mGluR1 antagonists as therapeutic agents | SCHERING CORPORATION (US) | 2009-02-03 | — | — | US | disclosed |
| EP-2004847-A2 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | Pentabase Aps (DK) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007104318-A2 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2007-09-20 | — | — | WO | disclosed |
| US-20060167029-A1 | mGluR1 Antagonists as therapeutic agents | SCHERING CORPORATION | 2006-07-27 | — | — | US | disclosed |
| US-20060009477-A1 | mGluR1 antagonists as therapeutic agents | SCHERING CORPORATION | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192178-A1 | mGluR1 ANTAGONISTS AS THERAPEUTIC AGENTS | GRM1, GRM4, GRIA1 | LIMK1 3031/4885CLK1 3660/4885CDC7 4254/4885 |
| US-20060167029-A1 | mGluR1 Antagonists as therapeutic agents | GRM1, GRM4, GRIA1 | LIMK1 3031/4885CLK1 3660/4885CDC7 4254/4885 |
| US-20060009477-A1 | mGluR1 antagonists as therapeutic agents | GRM1, GRM4, GRIA1 | LIMK1 2990/4885CLK1 3557/4885CDC7 4260/4885 |
| US-20090082336-A1 | mGluR1 Antagonists as Therapeutic Agents | GRM1, GRM4, GRIA1 | LIMK1 3031/4885CLK1 3660/4885CDC7 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.