SCHEMBL27182018

SCHEMBL27182018

CN(C)S(=O)(=O)c1ccc(Nc2nc3cc(C(=O)O)ccc3c3[nH]c(C(=O)O)cc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 17/20 0.47
EGFR P00533 2/20 0.45
KDR P35968 2/20 0.45
CSNK2A2 P19784 7/20 0.43
CSNK2B P67870 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27182006 0.85 CSNK2A1 (0.54) CSNK2A1CSNK2A2CSNK2B
SCHEMBL27182012 0.83 CSNK2A1 (0.62) CSNK2A1CSNK2A2CSNK2B
SCHEMBL27182015 0.81 CSNK2A1 (0.52) CSNK2A1CSNK2A2CSNK2B
SCHEMBL27182013 0.80 CSNK2A1 (0.51) CSNK2A1CSNK2A2CSNK2B
SCHEMBL27182010 0.79 CSNK2A1 (0.62) CSNK2A1CSNK2A2CSNK2B
SCHEMBL27182009 0.78 CSNK2A1 (0.64) CSNK2A1CSNK2A2CSNK2B
SCHEMBL27182007 0.77 CSNK2A1 (0.48) CSNK2A1CSNK2A2CSNK2B
SCHEMBL27182008 0.76 CSNK2A1 (0.65) CSNK2A1CSNK2A2CSNK2B
SCHEMBL27074478 0.76 CSNK2A1 (0.49) CSNK2A1CSNK2A2CSNK2B
SCHEMBL27182016 0.76 CSNK2A1 (0.66) CSNK2A1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11970496-B1 Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors King Faisal University (SA) 2024-04-30 US claimed
US-11958851-B1 Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors King Faisal University (SA) 2024-04-16 US claimed
US-11945818-B1 Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors King Faisal University (SA) 2024-04-02 US claimed
US-11970496-B1 Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors King Faisal University (SA) 2024-04-30 US disclosed
US-11958851-B1 Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors King Faisal University (SA) 2024-04-16 US disclosed
US-11945818-B1 Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors King Faisal University (SA) 2024-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970496-B1 Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors CSNK2A3, CSNK2A1, CSNK1G2 CSNK2A1 2/4885EGFR 1750/4885KDR 1462/4885
US-11945818-B1 Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors CSNK2A3, CSNK2A1, CSNK2A2 CSNK2A1 2/4885EGFR 2181/4885KDR 1755/4885
US-11958851-B1 Pyrrolo[3,2-c]quinoline compounds as CK2 inhibitors SKP2, CSNK2A3, CKS2 CSNK2A1 6/4885EGFR 2261/4885KDR 1516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.