SCHEMBL271833

SCHEMBL271833

BC1CC(OP(=O)(O)O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 13/20 0.37
P2RY4 P51582 4/20 0.37
POLB P06746 1/20 0.36
POLA1 P09884 1/20 0.36
POLD1 P28340 1/20 0.36
P2RY6 Q15077 1/20 0.36
P2RY1 P47900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4149125 0.89 P2RY2 (0.36) P2RY2P2RY4POLA1P2RY6
SCHEMBL21555520 0.88 P2RY2 (0.37) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL22002630 0.88 P2RY2 (0.37) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL21555519 0.88 P2RY2 (0.37) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL25141885 0.87 P2RY2 (0.37) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL18924567 0.87 P2RY2 (0.33) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL21506757 0.86 POLB (0.39) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL22327375 0.86 POLB (0.39) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL14364674 0.86 FBP1 (0.47) P2RY1
SCHEMBL271990 0.85 P2RY2 (0.37) P2RY2P2RY4POLBPOLA1POLD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed