SCHEMBL27188360

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27188313	0.90	PPARG (0.63)	PPARGRAB9ANPC1PTGDR2PTGES
	SCHEMBL30782719	0.87	PPARG (0.56)	PPARGRAB9ANPC1CHEK2PTGDR2
	SCHEMBL27188273	0.79	PPARG (1.00)	PPARGRORCPTGES
	SCHEMBL29327654	0.78	PPARG (0.52)	PPARGRAB9ANPC1RORCMCHR1
	SCHEMBL30782720	0.78	PPARG (0.56)	PPARGRAB9ANPC1PTGESHDAC1
	SCHEMBL29327607	0.78	PPARG (0.55)	PPARGRAB9ANPC1RORCPTGES
	SCHEMBL27188666	0.78	PPARG (0.45)	PPARGRAB9ANPC1CHEK2PTGDR2
	SCHEMBL27188325	0.78	KDM4E (0.56)	PPARGRAB9ANPC1CHEK2PTGDR2
	SCHEMBL31720872	0.78	NAMPT (0.58)	RAB9ANPC1CHEK2HDAC1HDAC8
	SCHEMBL26603124	0.78	NAMPT (0.58)	RAB9ANPC1CHEK2HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.