Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 2/20 | 0.53 |
| ▸ | MC1R | Q01726 | 2/20 | 0.53 |
| ▸ | MC3R | P41968 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27206530 | 1.00 | CYP2C19 (0.78) | CYP2C19ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL27191675 | 1.00 | CYP2C19 (0.78) | CYP2C19ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL27191698 | 0.89 | CYP2C19 (0.63) | CYP2C19ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL30749806 | 0.87 | CYP2C19 (0.60) | CYP2C19ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL30749808 | 0.87 | CYP2C19 (0.60) | CYP2C19ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL30882158 | 0.86 | MAPK1 (0.60) | CYP2C19ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL30882156 | 0.86 | MAPK1 (0.60) | CYP2C19ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL27191678 | 0.86 | CYP2C19 (0.59) | CYP2C19ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL30882160 | 0.85 | CYP2C19 (0.57) | CYP2C19ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL30882159 | 0.84 | CYP2C19 (0.56) | CYP2C19ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116896-A1 | HETEROATOM SUBSTITUTED CYCLIC AND ALKYL AMINES AS ACTIVATORS OF SEROTONIN RECEPTORS | ATAI THERAPEUTICS, INC. (US) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116896-A1 | HETEROATOM SUBSTITUTED CYCLIC AND ALKYL AMINES AS ACTIVATORS OF SEROTONIN RECEPTORS | HTR3B, HTR1A, HTR2B | CYP2C19 493/4885ADRA2A 41/4885ADRA2B 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.