Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5925778 | 0.87 | TDP1 (0.37) | EPHX2EPHX1MEN1KMT2AGAA | |
| SCHEMBL968705 | 0.85 | MEN1 (0.39) | EPHX2EPHX1MEN1KMT2ACCR1 | |
| SCHEMBL157125 | 0.85 | MEN1 (0.39) | EPHX2EPHX1MEN1KMT2ACCR1 | |
| SCHEMBL159477 | 0.84 | MEN1 (0.36) | EPHX2EPHX1MEN1KMT2AGAA | |
| SCHEMBL156223 | 0.84 | MEN1 (0.36) | EPHX2EPHX1MEN1KMT2AGAA | |
| SCHEMBL1538392 | 0.81 | MEN1 (0.37) | EPHX2EPHX1MEN1KMT2ACHRM2 | |
| SCHEMBL156155 | 0.81 | MEN1 (0.37) | EPHX2EPHX1MEN1KMT2ACHRM2 | |
| SCHEMBL157279 | 0.80 | MEN1 (0.36) | EPHX2EPHX1MEN1KMT2ACHRM2 | |
| SCHEMBL523968 | 0.80 | MEN1 (0.36) | EPHX2EPHX1MEN1KMT2ACHRM2 | |
| SCHEMBL11307514 | 0.80 | MEN1 (0.43) | EPHX2EPHX1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640190-A1 | MODIFIED NICOTINIC COMPOUNDS AND RELATED METHODS | Selecta Biosciences, Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012061717-A1 | MODIFIED NICOTINIC COMPOUNDS AND RELATED METHODS | SELECTA BIOSCIENCES, INC. (US) | 2012-05-10 | — | — | WO | disclosed |