Succinic Acid

Succinic Acid

SCHEMBL2719214

C=CCCCCCCCCCCCCCCCC.O=C(O)CCC(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4

The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.62
MAPT P10636 3/20 0.69
ABCC4 O15439 1/20 0.69
TSHR P16473 4/20 0.67
PPARG P37231 7/20 0.62
PPARD Q03181 7/20 0.62
PPARA Q07869 7/20 0.62
PTPN1 P18031 4/20 0.62
TERT O14746 3/20 0.62
TOP1 P11387 3/20 0.62
HSD17B10 Q99714 3/20 0.62
FABP4 P15090 3/20 0.62
TDP1 Q9NUW8 3/20 0.62
BLM P54132 2/20 0.62
ALOX15 P16050 2/20 0.62
KMT2A Q03164 2/20 0.62
GMNN O75496 1/20 0.62
USP2 O75604 1/20 0.62
LMNA P02545 1/20 0.62
CYP1A2 P05177 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL30558593 1.00 MAPT (0.69) MAPTABCC4TSHRPPARGPPARD
Succinic Acid SCHEMBL6731425 1.00 MAPT (0.69) MAPTABCC4TSHRPPARGPPARD
Succinic Acid SCHEMBL11142558 1.00 MAPT (0.69) MAPTABCC4TSHRPPARGPPARD
Succinic Acid SCHEMBL27368097 0.98 MAPT (0.67) MAPTABCC4TSHRPPARGPPARD
Hexanoate SCHEMBL17962235 0.94 MAPT (0.80) MAPTABCC4TSHRPPARGPPARD
Hexanoate SCHEMBL413538 0.94 MAPT (0.80) MAPTABCC4TSHRPPARGPPARD
Heptanoate SCHEMBL4053087 0.94 MAPT (0.80) MAPTABCC4TSHRPPARGPPARD
Stearic Acid SCHEMBL4022742 0.94 MAPT (0.80) MAPTABCC4TSHRPPARGPPARD
Hexanoate SCHEMBL16418126 0.94 MAPT (0.80) MAPTABCC4TSHRPPARGPPARD
Palmitic Acid SCHEMBL15537187 0.94 MAPT (0.80) MAPTABCC4TSHRPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2447344-B1 DIESEL COMPOSITION AND PROCESS FOR IMPROVING OXIDATION STABILITY OF BIODIESEL CHINA PETROLEUM & CHEM CORP (CN) 2019-07-24 EP claimed
US-20120124896-A1 Diesel Composition and Method of Increasing Biodiesel Oxidation Stability RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC (CN) 2012-05-24 US claimed
EP-2447344-A1 DIESEL COMPOSITION AND PROCESS FOR IMPROVING OXIDATION STABILITY OF BIODIESEL China Petroleum & Chemical Corporation (CN) 2012-05-02 EP claimed
EP-2447344-B1 DIESEL COMPOSITION AND PROCESS FOR IMPROVING OXIDATION STABILITY OF BIODIESEL CHINA PETROLEUM & CHEM CORP (CN) 2019-07-24 EP disclosed
CN-105829394-B Polyester resin, method for producing same, and toner 三菱化学株式会社 2019-02-12 CN disclosed
CN-105981209-B Non-aqueous electrolyte secondary battery 日产自动车株式会社 2018-12-04 CN disclosed
CN-103421579-A Preparation method of oxidized petrolatum barium soap oil soluble corrosion inhibitor HE SHUFENG 2013-12-04 CN disclosed
CN-103421583-A Preparation method of alkaline petroleum sulfonate oil soluble corrosion inhibitor HE SHUFENG 2013-12-04 CN disclosed
US-20120124896-A1 Diesel Composition and Method of Increasing Biodiesel Oxidation Stability RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC (CN) 2012-05-24 US disclosed
EP-2447344-A1 DIESEL COMPOSITION AND PROCESS FOR IMPROVING OXIDATION STABILITY OF BIODIESEL China Petroleum & Chemical Corporation (CN) 2012-05-02 EP disclosed