Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | PPARG | P37231 | 7/20 | 0.60 |
| ▸ | PPARA | Q07869 | 7/20 | 0.60 |
| ▸ | PPARD | Q03181 | 5/20 | 0.60 |
| ▸ | TERT | O14746 | 3/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | TOP1 | P11387 | 3/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL11142558 | 0.98 | MAPT (0.69) | MAPTABCC4TSHRPPARGPPARA | |
| Succinic Acid SCHEMBL6731425 | 0.98 | MAPT (0.69) | MAPTABCC4TSHRPPARGPPARA | |
| Succinic Acid SCHEMBL30558593 | 0.98 | MAPT (0.69) | MAPTABCC4TSHRPPARGPPARA | |
| Succinic Acid SCHEMBL2719214 | 0.98 | MAPT (0.69) | MAPTABCC4TSHRPPARGPPARA | |
| Hexanoate SCHEMBL17962235 | 0.92 | MAPT (0.80) | MAPTABCC4TSHRPPARGPPARA | |
| Hexanoate SCHEMBL413538 | 0.92 | MAPT (0.80) | MAPTABCC4TSHRPPARGPPARA | |
| Heptanoate SCHEMBL4053087 | 0.92 | MAPT (0.80) | MAPTABCC4TSHRPPARGPPARA | |
| Stearic Acid SCHEMBL4022742 | 0.92 | MAPT (0.80) | MAPTABCC4TSHRPPARGPPARA | |
| Hexanoate SCHEMBL16418126 | 0.92 | MAPT (0.80) | MAPTABCC4TSHRPPARGPPARA | |
| Undecylenic Acid SCHEMBL10818405 | 0.92 | MAPT (0.80) | MAPTABCC4TSHRPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103998022-A | Combination of plant extracts for improving skin color | MARY KAY INC | 2014-08-20 | — | — | CN | disclosed |
| CN-103987394-A | Skin care formulation | MARY KAY INC | 2014-08-13 | — | — | CN | disclosed |
| CN-103906524-A | Topical skin care formulations comprising plant extracts | MARY KAY INC | 2014-07-02 | — | — | CN | disclosed |
| CN-103764107-A | Sunscreen formulations | MARY KAY INC | 2014-04-30 | — | — | CN | disclosed |
| CN-103648479-A | Topical skin care formulations comprising plant extracts | MARY KAY INC | 2014-03-19 | — | — | CN | disclosed |
| CN-103635177-A | Lip stick | MARY KAY INC | 2014-03-12 | — | — | CN | disclosed |
| CN-103622852-A | Cosmetic composition | MARY KAY INC | 2014-03-12 | — | — | CN | disclosed |
| CN-103561754-A | Topical skin care formulations comprising plant extracts | MARY KAY INC | 2014-02-05 | — | — | CN | disclosed |
| CN-103458908-A | Sebum control and anti-acne composition | MARY KAY INC | 2013-12-18 | — | — | CN | disclosed |
| CN-103458867-A | Lip gloss | MARY KAY INC | 2013-12-18 | — | — | CN | disclosed |
| CN-101370473-A | Personal care compositions containing cationically modified starch and an anionic surfactant system | PROCTER & GAMBLE (US) | 2009-02-18 | — | — | CN | disclosed |
| CN-101244015-A | Beauty treatment preparation containing ethenyl pyrrolidone/acrylic acid copolymer | BEIERSDORF AG (DE) | 2008-08-20 | — | — | CN | disclosed |
| CN-100409831-C | Personal cleansing composition containing irregularly shaped particles and spherical particles | PROCTER & GAMBLE (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-101048131-A | Personal care compositions comprising non-guar galactomannan polymer derivatives and anionic surfactant systems | PROCTER & GAMBLE (US) | 2007-10-03 | — | — | CN | disclosed |
| CN-101048132-A | Personal care composition containing a non-guar galactomannan polymer derivative | PROCTER & GAMBLE (US) | 2007-10-03 | — | — | CN | disclosed |
| CN-1976739-A | Personal care compositions containing cationic modified starch and an anionic surfactant system | PROCTER & GAMBLE (US) | 2007-06-06 | — | — | CN | disclosed |
| CN-1723008-A | Personal cleansing compositions comprising irregularly shaped particles and spherically shaped particles | PROCTER & GAMBLE (US) | 2006-01-18 | — | — | CN | disclosed |
| CN-1646085-A | Shampoo containing a cationic guar derivative | PROCTER & GAMBLE (US) | 2005-07-27 | — | — | CN | disclosed |
| CN-1066032-C | Cosmetic capsules | UNILEVER NV (NL) | 2001-05-23 | — | — | CN | disclosed |
| CN-1090483-A | Cosmetic capsules | UNILEVER NV (NL) | 1994-08-10 | — | — | CN | disclosed |