Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 13/20 | 0.66 |
| ▸ | CYP11B1 | P15538 | 11/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 3/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27193217 | 0.84 | CHUK (0.61) | CYP17A1CDC7CHUKROCK2MAP4K4 | |
| SCHEMBL27193240 | 0.84 | CHUK (0.55) | CDC7CHUKROCK2MAP4K4GSK3B | |
| SCHEMBL22284875 | 0.79 | CYP17A1 (1.00) | CYP17A1CYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL23905177 | 0.77 | CYP17A1 (0.89) | CYP17A1CYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL27193266 | 0.77 | CHUK (0.45) | CDC7CHUKROCK2MAP4K4GSK3B | |
| SCHEMBL27193257 | 0.77 | JAK2 (0.48) | CDC7CHUKROCK2MAP4K4GSK3B | |
| SCHEMBL27193214 | 0.73 | CHEK2 (0.51) | CYP17A1CDC7CHUKROCK2MAP4K4 | |
| SCHEMBL3646839 | 0.73 | PLK4 (0.54) | CDC7CHUKROCK2MAP4K4CLK4 | |
| SCHEMBL5509666 | 0.73 | CYP17A1 (0.61) | CYP17A1CYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL29392318 | 0.72 | CYP17A1 (0.51) | CYP17A1CYP11B1CYP11B2CYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | SAINT LOUIS UNIVERSITY (US) | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116857-A1 | QUATERNARY AMMONIUM COMPOUNDS AS ANTIMICROBIALS | ABCC1, ARG1, SLC11A2 | CYP17A1 4610/4885CYP11B1 2556/4885CYP11B2 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.