SCHEMBL271933

SCHEMBL271933

CC(C)(C)N(C=O)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918168 0.72 TSHR (0.33) TSHR
SCHEMBL7189233 0.69
SCHEMBL276809 0.67 TSHR (0.32) TSHRTDP1
SCHEMBL276740 0.67 TSHR (0.32) TSHRTDP1
SCHEMBL277461 0.67 TSHR (0.30) TSHR
SCHEMBL59816 0.67
SCHEMBL5480721 0.65
SCHEMBL3560845 0.65
SCHEMBL150135 0.64
SCHEMBL11868739 0.62 TDP1 (0.38) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 784 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103316671-B Organic carbon monoxide-releasing molecules prepares method and the catalytic applications thereof of palladium carbon SHAANXI NORMAL UNIVERSITY (CN) 2015-12-23 CN claimed
CN-103316671-A Method for preparing palladium carbon by using organic carbon monoxide releasing molecule (CORM) and catalytic application of method UNIV SHAANXI NORMAL 2013-09-25 CN claimed
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US claimed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP claimed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO claimed
EP-0641356-B1 INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE GLAXO WELLCOME INC (US) 1998-04-22 EP claimed
US-5543406-A TREATING ANDROGEN RESPONSIVE OR MEDIATED DISEASE GLAXO WELLCOME, INC. (US) 1996-08-06 US claimed
US-5476743-A Thermoplastic resin, a charge director, a liquid component, an additive selected from cyclic carbonates, cyclic sulfones, cyclic sulfoxides and organic amides, pigments, and a charge adjuvant XEROX CORPORATION (US) 1995-12-19 US claimed
WO-1993013124-A1 INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE GLAXO INC. (US) 1993-07-08 WO claimed
EP-4622953-A1 PREPARATION OF 4-CYANOBENZOYL CHLORIDES FROM ALKALI METAL 4-CARBAMOYL-BENZOATES BASF SE (DE) 2025-10-01 EP disclosed
WO-2024128000-A1 ISOPOLYOXOTUNGSTATE SALT COMPOUND, SOLVATE THEREOF OR MIXTURE OF SAID COMPOUND AND SOLVATE, AND METHOD FOR PRODUCING SAID COMPOUND, SOLVATE OR MIXTURE 東京応化工業株式会社 2024-06-20 WO disclosed
US-11938233-B2 1,7-diaryl-1,6-heptadiene-3,5-dione derivatives, methods for the production and use thereof UNIVERSITÄTSKLINIKUM REGENSBURG (DE) 2024-03-26 US disclosed
WO-2024043261-A1 AZO COMPOUND OR SALT THEREOF, AND POLARIZING FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME 日本化薬株式会社 2024-02-29 WO disclosed
CN-114026199-B Polarized light emitting film, polarized light emitting panel and display device containing water-soluble coumarin compound or salt thereof 日本化药株式会社 2023-12-26 CN disclosed
EP-0064878-A1 Novel aniline derivatives, process for preparing the same and cardiotonic compositions containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1982-11-17 EP disclosed
US-4269998-A Production of dialkyl formamide UOP INC. (US) 1981-05-26 US disclosed
US-4016153-A Monoazo dyestuff mixtures derived from 2-amino-5-nitro-thiazole and bis-hydroxyalkylamino acklanilides reacted with acid halides and amides AMERICAN COLOR & CHEMICAL CORPORATION (US) 1977-04-05 US disclosed
US-4008212-A Monoazo dye mixtures derived from 7-amino-4-nitrobenzotriazole and bis-hydroxyalkylamino acylanilides reacted with acid halides and amides AMERICAN COLOR & CHEMICAL CORPORATION (US) 1977-02-15 US disclosed
US-3949088-A Substituted phenoxy propanol amines used for treating cardiovascular diseases SAMUELSSON BENNY ROGER 1976-04-06 US disclosed
US-3935016-A Silver halide color photographic materials containing 3-anilino-5-pyrazolone couplers FUJI PHOTO FILM COMPANY, LTD. (JA) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11938233-B2 1,7-diaryl-1,6-heptadiene-3,5-dione derivatives, methods for the production and use thereof DHPS, SQLE, CYP51A1 TSHR 4635/4885TDP1 1263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.