Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.77 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27194858 | 0.97 | CACNA1G (0.82) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 | |
| SCHEMBL27194859 | 0.89 | CACNA1G (0.71) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 | |
| SCHEMBL24709127 | 0.87 | CACNA1G (1.00) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 | |
| SCHEMBL4683069 | 0.85 | CYP2D6 (0.66) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 | |
| SCHEMBL27194860 | 0.85 | CACNA1G (0.66) | CACNA1GCACNA1HCYP3A4CYP2D6 | |
| SCHEMBL30849340 | 0.85 | CACNA1G (0.66) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 | |
| SCHEMBL27194843 | 0.85 | CACNA1G (0.66) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 | |
| SCHEMBL24709345 | 0.85 | CACNA1G (0.66) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 | |
| SCHEMBL24709558 | 0.85 | CACNA1G (0.98) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 | |
| SCHEMBL24709104 | 0.85 | CACNA1G (0.98) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353713-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Kinki University (JP) | 2024-04-17 | — | — | EP | disclosed |