Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.50 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27195726 | 0.88 | HDAC3 (0.58) | F10TNIKHDAC3HDAC8NPC1 | |
| SCHEMBL27195716 | 0.84 | HDAC1 (0.55) | HDAC3HDAC8NPC1RAB9AAURKA | |
| SCHEMBL27195794 | 0.83 | HDAC3 (0.58) | F10TNIKHDAC3HDAC8NPC1 | |
| SCHEMBL27195703 | 0.82 | TNIK (0.67) | F10TNIKNPC1RAB9AMEN1 | |
| SCHEMBL30863566 | 0.81 | TNIK (0.68) | TNIKNPC1RAB9AKMT2A | |
| SCHEMBL27195698 | 0.81 | TNIK (0.68) | TNIKNPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL30863433 | 0.80 | F10 (0.50) | F10TNIKHDAC3HDAC8NPC1 | |
| SCHEMBL30863414 | 0.79 | HDAC1 (0.46) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27195736 | 0.79 | AURKA (0.52) | F10HDAC3HDAC8NPC1RAB9A | |
| SCHEMBL22120013 | 0.77 | TNIK (0.56) | F10TNIKHDAC3HDAC8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353712-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2024-04-17 | — | — | EP | claimed |
| EP-4353712-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2024-04-17 | — | — | EP | disclosed |