SCHEMBL30863414

SCHEMBL30863414

CN1C[C@@H]2C[C@H]1CN2c1ccc(C(=O)Nc2ccc(Cl)c3ncccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC1 Q13547 2/20 0.46
▸ TNKS O95271 4/20 0.42
▸ TNKS2 Q9H2K2 3/20 0.42
▸ PDE4D Q08499 3/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ PABPC1 P11940 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ EIF4H Q15056 1/20 0.41
▸ MRGPRX1 Q96LB2 1/20 0.40
▸ PARP1 P09874 2/20 0.40
▸ PARP2 Q9UGN5 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ KDR P35968 1/20 0.40
▸ DRD2 P14416 1/20 0.38
▸ DRD4 P21917 1/20 0.38
▸ DRD3 P35462 1/20 0.38
▸ TP53 P04637 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27195707 0.79 F10 (0.50) MEN1KMT2A
SCHEMBL27195716 0.76 HDAC1 (0.55) HDAC1PDE4DL3MBTL1MEN1PABPC1
SCHEMBL16302065 0.71 HDAC6 (0.46) HDAC1MEN1KMT2ADRD2DRD4
SCHEMBL27195692 0.69 MAPT (0.49) HDAC1PDE4DL3MBTL1MEN1PABPC1
SCHEMBL27195726 0.67 HDAC3 (0.58) MEN1KMT2A
SCHEMBL16525559 0.67 PDE4D (0.66) PDE4DL3MBTL1MEN1PABPC1KMT2A
SCHEMBL28416079 0.66 KDR (0.62) L3MBTL1MEN1PABPC1KMT2AEIF4H
SCHEMBL7040443 0.65 MEN1 (0.66) PDE4DL3MBTL1MEN1PABPC1KMT2A
SCHEMBL24680837 0.65 HSD11B1 (0.53) DRD2DRD4DRD3
SCHEMBL24680826 0.65 HSD11B1 (0.53) DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP disclosed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO disclosed
Send feedback