Biphenyl

Biphenyl

SCHEMBL27200990

Oc1ccc2ccccc2c1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.81
ESR2 Q92731 10/20 0.79
ESR1 P03372 9/20 0.79
HSD17B1 P14061 2/20 0.63
HSD17B2 P37059 2/20 0.63
CYP3A4 P08684 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2B6 P20813 1/20 0.59
CYP2C19 P33261 1/20 0.59
MMP3 P08254 1/20 0.56
BCL2L1 Q07817 1/20 0.56
ALOX5 P09917 1/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Betanaphthol SCHEMBL8651479 0.93 CYP1A2 (0.94) CYP1A2ESR2ESR1HSD17B1HSD17B2
Betanaphthol SCHEMBL10977693 0.92 HSD17B1 (0.78) CYP1A2ESR2ESR1HSD17B1HSD17B2
Betanaphthol SCHEMBL27768280 0.90 CYP1A2 (0.90) CYP1A2ESR2ESR1HSD17B1HSD17B2
Betanaphthol SCHEMBL28781 0.90 CYP1A2 (1.00) CYP1A2ESR2ESR1HSD17B1HSD17B2
Betanaphthol SCHEMBL29658180 0.90 CYP1A2 (1.00) CYP1A2ESR2ESR1HSD17B1HSD17B2
Betanaphthol SCHEMBL239472 0.90 CYP1A2 (1.00) CYP1A2ESR2ESR1HSD17B1HSD17B2
Betanaphthol SCHEMBL11594695 0.90 CYP1A2 (1.00) CYP1A2ESR2ESR1HSD17B1HSD17B2
SCHEMBL5291228 0.88 ESR2 (1.00) CYP1A2ESR2ESR1HSD17B1HSD17B2
SCHEMBL14417356 0.88 ESR2 (1.00) CYP1A2ESR2ESR1HSD17B1HSD17B2
SCHEMBL29946599 0.88 ESR2 (1.00) CYP1A2ESR2ESR1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4357345-A1 CLY SERIES COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN PREPARATION OF DRUGS Nanjing Wellbest Pharmaceutical Co., Ltd (CN) 2024-04-24 EP disclosed