SCHEMBL27201095

SCHEMBL27201095

CCN(C)C=Nc1cc(C)c(Cc2cccc(C#N)c2)cc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.36
SCN8A Q9UQD0 1/20 0.35
HRH3 Q9Y5N1 1/20 0.34
MPO P05164 1/20 0.34
S1PR1 P21453 2/20 0.34
GLA P06280 1/20 0.33
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
PDCD1 Q15116 2/20 0.32
CD274 Q9NZQ7 2/20 0.32
MEP1A Q16819 1/20 0.31
MEP1B Q16820 1/20 0.31
DPP4 P27487 1/20 0.31
DPP9 Q86TI2 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
KMT2A Q03164 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27201184 0.90 S1PR1 (0.39) IDH1SCN8AHRH3MPOS1PR1
SCHEMBL27201073 0.87 CYP2A6 (0.36) IDH1HRH3CYP19A1CYP11B1CYP11B2
SCHEMBL27201130 0.85 CYP3A4 (0.38) MPO
SCHEMBL22232358 0.84 IDH1 (0.36) IDH1SCN8AHRH3MPOS1PR1
SCHEMBL22232360 0.84 IDH1 (0.36) IDH1SCN8AHRH3MPOS1PR1
SCHEMBL27201066 0.84 TAAR1 (0.38) KMT2A
SCHEMBL23613804 0.83 LDHA (0.35)
SCHEMBL30894762 0.83 LDHA (0.35)
SCHEMBL21495443 0.83
SCHEMBL23926272 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3525588-B1 4-SUBSTITUTED PHENYLAMIDINE DERIVATIVES AND THEIR USE TO PROTECT CROPS BY FIGHTING UNDESIRED PHYTOPATHOGENIC MICOORGANISMS PI INDUSTRIES LTD (IN) 2024-04-24 EP claimed