⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20438667 | 0.82 | DUT (0.40) | — | |
| SCHEMBL1085871 | 0.81 | MAPT (0.33) | — | |
| SCHEMBL1876097 | 0.81 | BACE1 (0.31) | — | |
| SCHEMBL9163997 | 0.79 | BACE1 (0.30) | — | |
| SCHEMBL2163046 | 0.79 | TSHR (0.40) | — | |
| SCHEMBL28790081 | 0.78 | MAPT (0.31) | — | |
| SCHEMBL10702400 | 0.78 | TSHR (0.36) | — | |
| SCHEMBL6470838 | 0.78 | — | — | |
| SCHEMBL22033623 | 0.77 | — | — | |
| SCHEMBL8451321 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | claimed |
| CN-119591621-A | Novel ecteinascidin derivatives, preparation method and application thereof, antibody drug conjugate and application thereof | 泰诚思(上海)生物医药有限公司 | 2025-03-11 | — | — | CN | disclosed |
| EP-3773563-B1 | PRODRUGS OF FUSED-BICYCLIC C5AR ANTAGONISTS | CHEMOCENTRYX INC (US) | 2024-10-16 | — | — | EP | disclosed |
| CN-111954525-B | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2023-12-26 | — | — | CN | disclosed |
| US-11608336-B2 | Prodrugs of fused-bicyclic C5aR antagonists | CHEMOCENTRYX, INC. (US) | 2023-03-21 | — | — | US | disclosed |
| CN-111393444-B | Preparation method of abacavir hydroxy acetate | 上海迪赛诺化学制药有限公司 | 2022-10-28 | — | — | CN | disclosed |
| EP-3448853-B1 | COMPOUNDS FOR MODULATING AQUAPORINS | APOGLYX AB (SE) | 2021-11-17 | — | — | EP | disclosed |
| EP-3448853-B1 | COMPOUNDS FOR MODULATING AQUAPORINS | APOGLYX AB (SE) | 2021-11-17 | — | — | EP | disclosed |
| US-20210052612-A1 | PRODRUGS OF FUSED-BICYCLIC C5aR ANTAGONISTS | CHEMOCENTRYX, INC. | 2021-02-25 | — | — | US | disclosed |
| CN-111954525-A | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2020-11-17 | — | — | CN | disclosed |
| US-4920148-A | C-29 oximinomilbemycin | CIBA-GEIGY CORPORATION (US) | 1990-04-24 | — | — | US | disclosed |
| US-4897416-A | 5-OXIMINO-13B-CARBONYLTHIOMILBEMYCIN DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |
| US-4871719-A | MILBEMYCIN | CIBA-GEIGY CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |
| US-4855317-A | Insecticides and parasiticides | CIBA-GEIGY CORPORATION (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0074758-B1 | 4A-SUBSTITUTED AVERMECTIN COMPOUNDS, THEIR PRODUCTION AND ANTIPARASITIC USE, AND COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1986-07-16 | — | — | EP | disclosed |
| US-4550160-A | Processes for the interconversion of C-076 compounds | MERCK & CO., INC. (US) | 1985-10-29 | — | — | US | disclosed |
| EP-0040913-B1 | 23-KETO DERIVATIVES OF C-076 COMPOUNDS, THEIR PREPARATION AND ANTI-PARASITIC USE | MERCK & CO. INC. (US) | 1984-07-25 | — | — | EP | disclosed |
| US-4328335-A | PARASITICIDES, CULTURE PRODUCT OF STREPTOMYCES REACTED WITH A THIOCARBONYL HALIDE | MERCK & CO., INC. (US) | 1982-05-04 | — | — | US | disclosed |
| EP-0040913-A1 | 23-Keto derivatives of C-076 compounds, their preparation and anti-parasitic use | MERCK & CO. INC. (US) | 1981-12-02 | — | — | EP | disclosed |
| US-4289760-A | ANTHELMINTICS, PARASITICIDES | MERCK & CO., INC. (US) | 1981-09-15 | — | — | US | disclosed |