⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31469886 | 1.00 | — | — | |
| SCHEMBL20746172 | 1.00 | — | — | |
| SCHEMBL13014875 | 1.00 | — | — | |
| SCHEMBL63773 | 1.00 | — | — | |
| SCHEMBL2917615 | 1.00 | — | — | |
| SCHEMBL1189649 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL34474911 | 0.97 | ALDH1A1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL1117277 | 0.97 | ALDH1A1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL15547550 | 0.97 | ALDH1A1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL15558585 | 0.97 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109302846-B | Indolinone compounds and their use in the treatment of fibrotic diseases | 莱斯彼维特有限公司 | 2021-05-11 | — | — | CN | claimed |
| US-20190337929-A1 | INDOLINONES COMPOUNDS AND THEIR USE IN THE TREATMENT OF FIBROTIC DISEASES | RESPIVERT LIMITED (GB) | 2019-11-07 | — | — | US | claimed |
| CN-109302846-A | Indolinone compounds and their use in the treatment of fibrotic diseases | 莱斯彼维特有限公司 | 2019-02-01 | — | — | CN | claimed |
| EP-2204394-B1 | PROCESS FOR PRODUCTION OF POLYESTER-CONTAINING FLEXIBLE POLYURETHANE FOAM, AND CATALYST COMPOSITION FOR USE IN THE PROCESS | TOSOH CORP (JP) | 2017-07-12 | — | — | EP | claimed |
| EP-2589601-B1 | COMPOUND FOR INHIBITING TYPE 5 PHOSPHODIESTERASE AND PREPARATION METHOD THEREOF | SUZHOU MAIDIXIAN PHARMACEUTICAL INC (CN) | 2015-09-09 | — | — | EP | claimed |
| US-8859565-B2 | Compound for inhibiting type 5 phosphodiesterase and preparation method thereof | ZHANG NAN (CN) | 2014-10-14 | — | — | US | claimed |
| US-20130116265-A1 | COMPOUND FOR INHIBITING TYPE 5 PHOSPHODIESTERASE AND PREPARATION METHOD THEREOF | ZHANG NAN (CN) | 2013-05-09 | — | — | US | claimed |
| EP-2589601-A1 | COMPOUND FOR INHIBITING TYPE 5 PHOSPHODIESTERASE AND PREPARATION METHOD THEREOF | Suzhou Maidixian Pharmaceutical Inc. (CN) | 2013-05-08 | — | — | EP | claimed |
| US-20100256249-A1 | METHOD FOR PRODUCING POLYESTER TYPE FLEXIBLE POLYURETHANE FOAM, AND CATALYST COMPOSITION TO BE USED THEREFOR | TOSOH CORPORATION (JP) | 2010-10-07 | — | — | US | claimed |
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | claimed |
| EP-2204394-A1 | PROCESS FOR PRODUCTION OF POLYESTER-CONTAINING FLEXIBLE POLYURETHANE FOAM, AND CATALYST COMPOSITION FOR USE IN THE PROCESS | Tosoh Corporation (JP) | 2010-07-07 | — | — | EP | claimed |
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | claimed |
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | claimed |
| US-20060128685-A1 | Pyrazole derivative | DAIICHI PHARMACEUTICAL CO., LTD., (JP) | 2006-06-15 | — | — | US | claimed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | claimed |
| EP-1591443-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-02 | — | — | EP | claimed |
| CN-117886824-B | 2, 3-Dihydropyrimido [4,5-d ] pyrimidine-4 (1H) -ketone derivative, preparation method and application thereof | 四川大学华西医院 | 2026-05-15 | — | — | CN | disclosed |
| EP-4683934-A1 | SYSTEM | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2026-01-28 | — | — | EP | disclosed |
| WO-1993001181-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS | THE UPJOHN COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |
| US-5055581-A | Dehydrochlorination reaction between n-alkyl substituted piperazine and bis(-chloroalkyl) ether; useful for urethane forming reaction | SAN-APRO LIMITED (JP) | 1991-10-08 | — | — | US | disclosed |