Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 3/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2718876 | 0.80 | GAA (1.00) | GAARXFP1POLBTDP1KMT2A | |
| SCHEMBL29477262 | 0.80 | GAA (1.00) | GAARXFP1POLBTDP1KMT2A | |
| SCHEMBL6954598 | 0.78 | GAA (0.63) | GAAPOLBKMT2AALDH1A1KDM4E | |
| SCHEMBL6947705 | 0.77 | GAA (0.62) | GAAPOLBKMT2AMAPTALDH1A1 | |
| SCHEMBL7077522 | 0.77 | GAA (0.61) | GAAPOLBKMT2AALDH1A1KDM4E | |
| SCHEMBL8307191 | 0.76 | GAA (0.61) | GAAPOLBKMT2AMAPTALDH1A1 | |
| SCHEMBL7430586 | 0.75 | GAA (0.60) | GAAPOLBTDP1KMT2AMAPT | |
| SCHEMBL6951357 | 0.75 | GAA (0.60) | GAAPOLBKMT2AALDH1A1TP53 | |
| SCHEMBL29059034 | 0.75 | GAA (0.60) | GAA | |
| SCHEMBL30555215 | 0.75 | GAA (0.60) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061597-A1 | ALPHA-GLUCOSIDASE BINDERS AND METHODS OF THEIR USE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH (US) | 2012-05-10 | — | — | WO | disclosed |