Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947705 | 0.99 | GAA (0.62) | GAAEGFRHTR2CKDM4EMAPT | |
| SCHEMBL6954598 | 0.87 | GAA (0.63) | GAAHTR2CKDM4EPOLBMEN1 | |
| SCHEMBL7077522 | 0.85 | GAA (0.61) | GAAHTR2CKDM4EPOLBMEN1 | |
| SCHEMBL7430586 | 0.81 | GAA (0.60) | GAAKDM4EMAPTPOLBMEN1 | |
| SCHEMBL6951357 | 0.81 | GAA (0.60) | GAAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7079432 | 0.78 | GAA (0.54) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6949259 | 0.77 | GAA (0.53) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6948048 | 0.77 | ALDH1A1 (0.57) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7442190 | 0.77 | GAA (0.55) | GAA | |
| SCHEMBL2720518 | 0.76 | GAA (1.00) | GAAKDM4EMAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078731-A1 | QUINOLINE-CARBOXYLIC ACIDS AND THE DERIVATIVES THEREOF, A FOCUSED LIBRARY | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE', LTD. (RU) | 2004-09-16 | — | — | WO | disclosed |