Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 16/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10080938 | 0.86 | GAA (0.75) | GAAKMT2ARXFP1POLBTDP1 | |
| SCHEMBL10080936 | 0.85 | GAA (0.74) | GAAKMT2ARXFP1POLBTDP1 | |
| SCHEMBL2718876 | 0.84 | GAA (1.00) | GAAKMT2ARXFP1POLBTDP1 | |
| SCHEMBL29477262 | 0.84 | GAA (1.00) | GAAKMT2ARXFP1POLBTDP1 | |
| SCHEMBL10080667 | 0.81 | GAA (0.68) | GAAKMT2ARXFP1POLBTDP1 | |
| SCHEMBL10080937 | 0.80 | GAA (0.67) | GAAKMT2ARXFP1POLBTDP1 | |
| SCHEMBL10080939 | 0.78 | GAA (0.64) | GAAKMT2ARXFP1POLBTDP1 | |
| SCHEMBL2956043 | 0.75 | MAPT (0.61) | GAAKMT2ARXFP1POLBTDP1 | |
| SCHEMBL2718633 | 0.75 | GAA (0.67) | GAAKMT2ARXFP1POLBTDP1 | |
| SCHEMBL2717892 | 0.74 | GAA (1.00) | GAAKMT2ARXFP1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061597-A1 | ALPHA-GLUCOSIDASE BINDERS AND METHODS OF THEIR USE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH (US) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012061597-A1 | ALPHA-GLUCOSIDASE BINDERS AND METHODS OF THEIR USE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH (US) | 2012-05-10 | — | — | WO | disclosed |