Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10081899 | 0.85 | MGLL (0.60) | GAAKMT2APOLBMGLLALDH1A1 | |
| SCHEMBL10081895 | 0.85 | GAA (0.53) | GAAKMT2APOLBRXFP1TDP1 | |
| SCHEMBL2718633 | 0.84 | GAA (0.67) | GAAKMT2APOLBRXFP1TDP1 | |
| SCHEMBL2720573 | 0.81 | GAA (1.00) | GAAKMT2APOLBRXFP1TDP1 | |
| SCHEMBL10081888 | 0.80 | MGLL (0.47) | GAAKMT2AMGLLMAPT | |
| SCHEMBL10081883 | 0.78 | MGLL (0.49) | GAAKMT2AMGLLMEN1 | |
| SCHEMBL10081885 | 0.77 | MGLL (0.52) | GAAKMT2APOLBMGLLALDH1A1 | |
| SCHEMBL10081891 | 0.77 | KCNH2 (0.45) | GAAKMT2AMGLLALDH1A1SMN1; SMN2 | |
| SCHEMBL2729628 | 0.74 | NR3C1 (0.69) | GAAKMT2APOLBRXFP1TDP1 | |
| SCHEMBL29477262 | 0.74 | GAA (1.00) | GAAKMT2APOLBRXFP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061597-A1 | ALPHA-GLUCOSIDASE BINDERS AND METHODS OF THEIR USE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH (US) | 2012-05-10 | — | — | WO | disclosed |