Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.89 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.89 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CCR3 | P51677 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30079694 | 0.94 | CACNA1G (1.00) | CACNA1GCACNA1HSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL24708724 | 0.94 | CACNA1G (1.00) | CACNA1GCACNA1HSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL24709104 | 0.93 | CACNA1G (0.98) | CACNA1GCACNA1HSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL24709347 | 0.93 | CACNA1G (0.98) | CACNA1GCACNA1HSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL24708803 | 0.93 | CACNA1G (0.98) | CACNA1GCACNA1HSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL24709558 | 0.93 | CACNA1G (0.98) | CACNA1GCACNA1HSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL24708732 | 0.90 | CACNA1G (0.87) | CACNA1GCACNA1HSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL24709338 | 0.90 | CACNA1G (0.87) | CACNA1GCACNA1HSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL24709352 | 0.90 | CACNA1G (0.87) | CACNA1GCACNA1HSIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL24709556 | 0.89 | CACNA1G (0.89) | CACNA1GCACNA1HSIGMAR1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353713-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Kinki University (JP) | 2024-04-17 | — | — | EP | disclosed |