SCHEMBL27207489

SCHEMBL27207489

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cnc2n1CC=CCNc1c(N)cc(C(N)=O)cc1OC

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 19/20 0.68
CYP3A4 P08684 1/20 0.56
ENPP1 P22413 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27204004 1.00 STING1 (0.68) STING1CYP3A4ENPP1
SCHEMBL28639271 0.91 STING1 (0.62) STING1CYP3A4ENPP1
SCHEMBL28639272 0.91 STING1 (0.62) STING1CYP3A4ENPP1
SCHEMBL27204069 0.90 STING1 (0.64) STING1CYP3A4ENPP1
SCHEMBL27204000 0.90 STING1 (0.64) STING1CYP3A4ENPP1
SCHEMBL27207233 0.88 STING1 (0.66) STING1CYP3A4
SCHEMBL21630050 0.88 STING1 (0.66) STING1CYP3A4
SCHEMBL21616437 0.88 STING1 (0.84) STING1CYP3A4
SCHEMBL27204051 0.88 STING1 (0.84) STING1CYP3A4
SCHEMBL22121447 0.87 STING1 (0.66) STING1CYP3A4ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240132493-A1 IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS FULGENT GENETICS INC (US) 2024-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132493-A1 IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS STING1, IRF3, MAVS STING1 1/4885CYP3A4 3589/4885ENPP1 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.