SCHEMBL272125

SCHEMBL272125

BC1CC(OS(=O)(=O)Oc2ccc(C)cc2)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)S1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 18/20 0.36
P2RY4 P51582 2/20 0.33
BTN3A1 O00481 1/20 0.32
POLB P06746 1/20 0.31
POLA1 P09884 1/20 0.31
POLD1 P28340 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272286 0.82 P2RY2 (0.40) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL271940 0.76 P2RY2 (0.34) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL272436 0.74 P2RY2 (0.33) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL272435 0.74 P2RY2 (0.33) P2RY2POLBPOLA1POLD1
SCHEMBL271939 0.74 P2RY2 (0.33) P2RY2P2RY4BTN3A1
SCHEMBL272126 0.74 P2RY2 (0.39) P2RY2P2RY4POLBPOLA1POLD1
SCHEMBL271999 0.71 P2RY2 (0.35) P2RY2P2RY4BTN3A1
SCHEMBL18603980 0.71 P2RY2 (0.35) P2RY2P2RY4BTN3A1
SCHEMBL271982 0.71 P2RY2 (0.39) P2RY2P2RY4
SCHEMBL18604216 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed