Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 17/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | POLD1 | P28340 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 6/20 | 0.30 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272286 | 0.94 | P2RY2 (0.40) | P2RY2POLBPOLA1POLD1P2RY4 | |
| SCHEMBL272435 | 0.89 | P2RY2 (0.33) | P2RY2POLBPOLA1POLD1 | |
| SCHEMBL272436 | 0.87 | P2RY2 (0.33) | P2RY2POLBPOLA1POLD1P2RY4 | |
| SCHEMBL18852752 | 0.77 | P2RY2 (0.41) | P2RY2POLBPOLA1POLD1P2RY4 | |
| SCHEMBL18604216 | 0.76 | — | — | |
| SCHEMBL272125 | 0.76 | P2RY2 (0.36) | P2RY2POLBPOLA1POLD1P2RY4 | |
| SCHEMBL272126 | 0.74 | P2RY2 (0.39) | P2RY2POLBPOLA1POLD1P2RY4 | |
| SCHEMBL271939 | 0.72 | P2RY2 (0.33) | P2RY2P2RY4P2RY6 | |
| SCHEMBL271898 | 0.72 | P2RY2 (0.32) | P2RY2P2RY4P2RY6 | |
| SCHEMBL272343 | 0.71 | P2RY2 (0.36) | P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133669-B2 | Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid | TRILINK BIOTECHNOLOGIES (US) | 2012-03-13 | — | — | US | disclosed |
| US-8133669-B2 | Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid | TRILINK BIOTECHNOLOGIES (US) | 2012-03-13 | — | — | US | disclosed |
| US-20100003724-A1 | CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID | TriLink Bio Technologies | 2010-01-07 | — | — | US | disclosed |
| US-20100003724-A1 | CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID | TriLink Bio Technologies | 2010-01-07 | — | — | US | disclosed |