SCHEMBL27214734

SCHEMBL27214734

Oc1ccccc1C=Nc1ccc2ccccc2c1-c1c(N=Cc2ccccc2O)ccc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.61
CA2 P00918 2/20 0.61
CA9 Q16790 1/20 0.61
POLB P06746 4/20 0.59
L3MBTL1 Q9Y468 3/20 0.59
CRHBP P24387 1/20 0.55
CRHR2 Q13324 1/20 0.55
KMT2A Q03164 8/20 0.53
ALDH1A1 P00352 7/20 0.53
MAPT P10636 7/20 0.53
MEN1 O00255 6/20 0.53
KDM4E B2RXH2 5/20 0.53
GAA P10253 3/20 0.53
ATM Q13315 2/20 0.53
DHODH Q02127 1/20 0.52
SIRT2 Q8IXJ6 1/20 0.51
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12786273 1.00 CA12 (0.61) CA12CA2CA9POLBL3MBTL1
SCHEMBL29862789 1.00 CA12 (0.61) CA12CA2CA9POLBL3MBTL1
SCHEMBL12786260 0.95 CA12 (0.56) CA12CA2CA9POLBL3MBTL1
SCHEMBL13051325 0.89 POLB (0.76) CA12CA2CA9POLBL3MBTL1
SCHEMBL624828 0.87 L3MBTL1 (0.63) CA12CA2CA9POLBL3MBTL1
SCHEMBL10049044 0.87 L3MBTL1 (0.63) CA12CA2CA9POLBL3MBTL1
SCHEMBL15377777 0.86 L3MBTL1 (0.61) CA12CA2CA9POLBL3MBTL1
SCHEMBL22914874 0.84 KMT2A (0.58) POLBL3MBTL1KMT2AALDH1A1MAPT
SCHEMBL30704461 0.84 KMT2A (0.58) POLBL3MBTL1KMT2AALDH1A1MAPT
SCHEMBL12809855 0.83 L3MBTL1 (0.82) CA12CA2CA9POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150520-A1 ALTERNATING POLY(LACTIC-CO-GLYCOLIC ACID) AND METHODS OF MAKING AND USING SAME UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2024-05-09 US claimed
US-20240150520-A1 ALTERNATING POLY(LACTIC-CO-GLYCOLIC ACID) AND METHODS OF MAKING AND USING SAME UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2024-05-09 US disclosed