Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRAS | P01112 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PNP | P00491 | 2/20 | 0.35 |
| ▸ | GAPDH | P04406 | 2/20 | 0.34 |
| ▸ | PAX3 | P23760 | 1/20 | 0.33 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18490686 | 1.00 | MEN1 (0.47) | MEN1USP2POLBKMT2AHRAS | |
| SCHEMBL22401432 | 0.93 | MEN1 (0.55) | MEN1USP2POLBKMT2AHRAS | |
| SCHEMBL18510812 | 0.93 | MEN1 (0.40) | MEN1USP2POLBKMT2AHRAS | |
| SCHEMBL21925882 | 0.93 | KDM4E (0.41) | MEN1USP2POLBKMT2AHRAS | |
| SCHEMBL27251023 | 0.87 | MEN1 (0.45) | MEN1USP2POLBKMT2AHRAS | |
| SCHEMBL22883454 | 0.87 | MEN1 (0.48) | MEN1USP2POLBKMT2AHRAS | |
| SCHEMBL18490666 | 0.85 | MEN1 (0.51) | MEN1USP2POLBKMT2AHRAS | |
| SCHEMBL27216182 | 0.85 | MEN1 (0.51) | MEN1USP2POLBKMT2AHRAS | |
| SCHEMBL22381608 | 0.85 | MEN1 (0.36) | MEN1USP2POLBKMT2AHRAS | |
| SCHEMBL18520875 | 0.85 | MEN1 (0.36) | MEN1USP2POLBKMT2AHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334745-B1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-15 | — | — | EP | disclosed |