Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PAX3 | P23760 | 1/20 | 0.34 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.34 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.33 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.33 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.32 |
| ▸ | HRAS | P01112 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18510812 | 0.94 | MEN1 (0.40) | KDM4EPOLBMEN1USP2KMT2A | |
| SCHEMBL18490686 | 0.93 | MEN1 (0.47) | KDM4EPOLBMEN1USP2KMT2A | |
| SCHEMBL27216181 | 0.93 | MEN1 (0.47) | KDM4EPOLBMEN1USP2KMT2A | |
| SCHEMBL27251023 | 0.89 | MEN1 (0.45) | KDM4EPOLBMEN1USP2KMT2A | |
| SCHEMBL22401432 | 0.87 | MEN1 (0.55) | KDM4EPOLBMEN1USP2KMT2A | |
| SCHEMBL22034266 | 0.84 | KDM4E (0.42) | KDM4ETAS1R3TAS1R1 | |
| SCHEMBL21877963 | 0.84 | KDM4E (0.42) | KDM4ETAS1R3TAS1R1 | |
| SCHEMBL31401856 | 0.84 | KDM4E (0.52) | KDM4EMEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL18521374 | 0.82 | KDM4E (0.43) | KDM4EPOLBTAS1R3TAS1R1LMNA | |
| SCHEMBL18490578 | 0.82 | KDM4E (0.43) | KDM4EPOLBTAS1R3TAS1R1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161864-B2 | Sting agonists | Venenum Biodesign, LLC (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200131209-A1 | NOVEL STING AGONISTS | Venenum Biodesign, LLC | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131209-A1 | NOVEL STING AGONISTS | STING1, CGAS, TBK1 | KDM4E 2514/4885POLB 3287/4885MEN1 1929/4885 |
| US-11161864-B2 | Sting agonists | STING1, IRF3, CGAS | KDM4E 2453/4885POLB 2984/4885MEN1 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.