Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 12/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | PDE9A | O76083 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217953 | 0.92 | CYP1A2 (0.42) | EGFRCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL27217920 | 0.91 | ERBB2 (0.44) | EGFRPDE9AKMT2A | |
| SCHEMBL30813419 | 0.90 | EPHX2 (0.44) | EGFRCYP3A4ALDH1A1PDE9ACYP2C9 | |
| SCHEMBL27217855 | 0.90 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C19CYP2D6CLK4 | |
| SCHEMBL30813549 | 0.88 | CLK4 (0.48) | EGFRCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL27217928 | 0.88 | CLK4 (0.48) | EGFRCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL27218011 | 0.87 | CYP1A2 (0.41) | EGFRCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL30813425 | 0.86 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C19CYP2D6CLK4 | |
| SCHEMBL27217798 | 0.86 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C19CYP2D6CLK4 | |
| SCHEMBL30813465 | 0.83 | RET (0.40) | EGFRCYP1A2CYP3A4CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158394-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | 2024-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158394-A1 | NEK7 INHIBITORS | NEK7, NEK5, NEK1 | EGFR 4857/4885CYP1A2 4011/4885CYP3A4 3360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.