Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 10/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | INSR | P06213 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | ROS1 | P08922 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | FER | P16591 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217928 | 1.00 | CLK4 (0.48) | CLK4MAPK1CDC7PLK4DYRK3 | |
| SCHEMBL27217855 | 0.95 | CYP1A2 (0.46) | CLK4MAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30813425 | 0.90 | CYP1A2 (0.45) | CLK4MAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27217798 | 0.90 | CYP1A2 (0.45) | CLK4MAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27217936 | 0.88 | CYP1A2 (0.42) | CLK4MAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30813667 | 0.88 | CYP1A2 (0.42) | CLK4MAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27217779 | 0.88 | EGFR (0.41) | CLK4MAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30813353 | 0.86 | CYP1A2 (0.43) | CLK4MAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27218013 | 0.86 | CYP1A2 (0.43) | CLK4MAPK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL27217878 | 0.86 | CYP1A2 (0.43) | CLK4MAPK1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |