Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217812 | 0.91 | SRC (0.34) | — | |
| SCHEMBL27217841 | 0.89 | FLT3 (0.38) | — | |
| SCHEMBL30813485 | 0.86 | RET (0.35) | RETNEK7 | |
| SCHEMBL27217684 | 0.85 | KDR (0.35) | RET | |
| SCHEMBL27217890 | 0.84 | RIPK2 (0.40) | RET | |
| SCHEMBL27217802 | 0.84 | EGFR (0.30) | — | |
| SCHEMBL27217847 | 0.83 | SRC (0.38) | RET | |
| SCHEMBL27217699 | 0.82 | RAB9A (0.32) | RETNEK7 | |
| SCHEMBL27217746 | 0.82 | NEK7 (0.37) | RETNEK7 | |
| SCHEMBL30813586 | 0.82 | RET (0.35) | RETNEK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158394-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | 2024-05-16 | — | — | US | disclosed |
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158394-A1 | NEK7 INHIBITORS | NEK7, NEK5, NEK1 | RET 2117/4885NEK7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.