Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2722688 | 0.99 | DRD2 (0.70) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL3653432 | 0.85 | DRD2 (0.54) | DRD2DRD3 | |
| SCHEMBL2720644 | 0.84 | DRD2 (0.51) | DRD2DRD3 | |
| SCHEMBL2722841 | 0.84 | DRD2 (0.71) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL2720637 | 0.84 | DRD2 (0.51) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL2720683 | 0.83 | DRD2 (0.70) | DRD2DRD3 | |
| SCHEMBL2351597 | 0.81 | DRD2 (1.00) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL2348887 | 0.81 | DRD2 (0.98) | DRD2DRD3 | |
| SCHEMBL2350286 | 0.81 | DRD2 (1.00) | DRD2DRD3 | |
| SCHEMBL2354612 | 0.79 | DRD2 (1.00) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492540-B2 | 1,2,4,-triazin-3,5-dione compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor | ABBOTT GMBH & CO. KG (DE) | 2013-07-23 | — | — | US | claimed |
| EP-2217593-B1 | 1,2,4,-TRIAZIN-3,5-DIONE COMPOUNDS FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO KG (DE) | 2012-05-02 | — | — | EP | claimed |