SCHEMBL272203

SCHEMBL272203

BC1SC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C2OC(=S)OC12

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 19/20 0.38
P2RY4 P51582 5/20 0.38
POLG P54098 1/20 0.33
P2RY6 Q15077 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271908 0.76 P2RY2 (0.39) P2RY2P2RY4P2RY6
SCHEMBL301058 0.71 P2RY2 (0.39) P2RY2P2RY4P2RY6
SCHEMBL272012 0.69 P2RY2 (0.31) P2RY2P2RY4
SCHEMBL271906 0.68 P2RY2 (0.36) P2RY2P2RY4P2RY6
SCHEMBL272023 0.67 P2RY2 (0.33) P2RY2P2RY4P2RY6
SCHEMBL272020 0.66 P2RY2 (0.32) P2RY2P2RY4P2RY6
SCHEMBL271999 0.64 P2RY2 (0.35) P2RY2P2RY4
SCHEMBL18866653 0.64 P2RY2 (0.38) P2RY2P2RY4POLGP2RY6
SCHEMBL272204 0.64 P2RY2 (0.39) P2RY2P2RY4P2RY6
SCHEMBL19174881 0.63 P2RY2 (0.36) P2RY2P2RY4POLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294076-B1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED REPLICATION OF NUCLEIC ACID TRILINK BIOTECHNOLOGIES (US) 2017-03-08 EP disclosed
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed