SCHEMBL271906

SCHEMBL271906

BC1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)S)C2OC(=S)OC12

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 13/20 0.36
P2RY6 Q15077 7/20 0.36
P2RY4 P51582 6/20 0.36
P2RY12 Q9H244 3/20 0.33
P2RX3 P56373 1/20 0.32
ENPP1 P22413 1/20 0.32
P2RY14 Q15391 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271908 0.91 P2RY2 (0.39) P2RY2P2RY6P2RY4P2RX3
SCHEMBL272020 0.85 P2RY2 (0.32) P2RY2P2RY6P2RY4
SCHEMBL272023 0.84 P2RY2 (0.33) P2RY2P2RY6P2RY4P2RY12P2RX3
SCHEMBL272204 0.80 P2RY2 (0.39) P2RY2P2RY6P2RY4P2RX3
SCHEMBL301058 0.76 P2RY2 (0.39) P2RY2P2RY6P2RY4P2RX3
SCHEMBL18602932 0.74
SCHEMBL13574842 0.69 FBP1 (0.53) P2RY2P2RY6P2RY4P2RX3
SCHEMBL272525 0.68 P2RY2 (0.39) P2RY2P2RY6P2RY4P2RX3
SCHEMBL272203 0.68 P2RY2 (0.38) P2RY2P2RY6P2RY4
SCHEMBL12374598 0.66 FBP1 (0.53) P2RY2P2RY4P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed