Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750649 | 0.83 | KDM4E (0.58) | KDM4EHPGDTSHRALDH1A1HSD17B10 | |
| SCHEMBL27445624 | 0.83 | KDM4E (0.58) | KDM4EHPGDTSHRALDH1A1HSD17B10 | |
| SCHEMBL549420 | 0.79 | KDM4E (0.54) | KDM4EHPGDTSHRALDH1A1HSD17B10 | |
| SCHEMBL29287849 | 0.79 | KDM4E (0.54) | KDM4EHPGDTSHRALDH1A1HSD17B10 | |
| SCHEMBL27982454 | 0.79 | KDM4E (0.54) | KDM4EHPGDTSHRALDH1A1HSD17B10 | |
| SCHEMBL11328033 | 0.79 | KDM4E (0.54) | KDM4EHPGDTSHRALDH1A1HSD17B10 | |
| Oxalic Acid SCHEMBL23496612 | 0.78 | HPGD (0.54) | KDM4EHPGDTSHRALDH1A1HSD17B10 | |
| SCHEMBL28195080 | 0.78 | CES2 (0.54) | KDM4EHPGDTSHRALDH1A1TP53 | |
| SCHEMBL11790045 | 0.78 | TSHR (0.58) | KDM4EHPGDTSHRALDH1A1HSD17B10 | |
| SCHEMBL7173445 | 0.76 | KDM4E (0.50) | KDM4EHPGDTSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012051708-A1 | ANTI-BACTERIAL PYRUVATE KINASE MODULATOR COMPOUNDS, COMPOSITIONS, USES, AND METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-04-26 | — | — | WO | disclosed |